Back in the 1970s I attempted follow in intellectual footsteps of the now largely discredited sociological cultural anthropologist, Carlos Castaneda. I tested on myself several extracts from indigenous plants and mushrooms. These naturally occurring drugs discovered by shamans were as follows:
- Jimsonweed (Datura stramonium) which I may remember contains the tropane alkaloid: atropine. Atropine has been used in medicine to dilate the pupils of human eyes for study by an ophthalmologist. It is also a hallucinogenic alkaloid. The antagonist of atropine is scopolamine.
- Amanita muscaria (the fly agaric also known as a mushroom) contains a few hallucinogenic alkaloids including an insecticide that kills flies that feed on the mushroom.
- Stropharia cubensis a mushroom that contains the hallucinogenic alkaloids psilocybin and psilocin.
In the halcyon days of my youth 17 – 21, I planned on becoming a pharmacognosist that is a scientist that hunts for useful alkaloids to be found in nature. To follow in footsteps Castaneda and Manske (“The Alkaloids” an encyclopedia of useful drugs from the natural world in 70+ volumes), I would need to be well trained in botany, ecology, pharmacology, plant physiology, etc. Good thing I did not go down that path since I might have accidentally overdosed on a new alkaloid.
I have an anecdote I like to retell about obtaining samples of the mushrooms 3 above. There was a farmer on Whitesville Road next to the old Troup County High School who had cows in a large pasture. I knew that in August there would be psilocybin yielding mushrooms growing out of cow manure. A male partner in crime of mine and I just casually went up to farmhouse door and politely lied to the farmer about being students of mycology from Auburn University and we would like to gather some mushroom samples from his pasture. He said “Sure, just do not disturb my cows”.